M. Sharon Stack
Kleiderer-Pezold Professor of Biochemistry
An outstanding scholar and nationally known cancer researcher, M. Sharon Stack is the Kleiderer-Pezold Professor of Biochemistry and Ann F. Dunne and Elizabeth M. Riley Director of the Mike and Josie Harper Cancer Research Institute.
Prior to joining Notre Dame’s faculty in 2011, Stack was professor and vice chair for research in the Department of Pathology and Anatomical Sciences and a professor of cancer research at the University of Missouri School of Medicine. Stack also served as a professor in the Department of Cell and Molecular Biology at Northwestern University Feinberg School of Medicine.
Her interests include proteinase regulation, cell-cell and cell-matrix adhesion, ovarian and oral tumors, mechanotransduction, and extracellular matrix remodeling. Her research focus is in the area of molecular mechanisms of metastasis.
Stack has served as a full member of the National Institutes of Health/National Cancer Institute Tumor Progression and Metastasis (TPM) study section and currently performs ad hoc review service for both TPM and Tumor Microenvironment as well as intramural review for the National Institute of Dental and Craniofacial Research (NIDCR). She also has served on review panels organized by the U.S. Army Medical Research and Material Command for all three of their cancer programs: breast, prostate and ovarian, since 1994, and is currently a member of the Integration Panel for the Department of Defense Ovarian Cancer Research Program. Stack also is on the editorial board of Cancer Research and is a retired member of the Journal of Biological Chemistry and the Biochemical Journal editorial boards.
Professor Stack earned her bachelor of science in Biochemistry from Clemson University in 1981, followed by a Fulbright Fellowship year in Bonn, Germany. She earned a master of science in Biomedical Sciences from East Tennessee State University in 1985. In 1989, she received her doctoral degree in biochemistry from the University of Louisville and completed postdoctoral training in biochemical pathology at Duke University Medical Center. She also served for several years as a research assistant professor at the Duke Medical Center prior to joining the faculty at Northwestern University Feinberg Medical School.
This professorship was established in 2012 with earnings from the original Kleiderer-Pezold Professorship, which was named for donors Dr. Ervin C. Kleiderer and Dr. Margaret Pezold Kleiderer. Ervin, a distinguished Indianapolis research chemist, was the executive director of research, development, and control at Eli Lilly and Co. Both Ervin and Margaret were active on Notre Dame’s advisory councils.