Navari Family Professor of Life Sciences
Shahriar Mobashery is a world-renowned expert on antibiotics, antibiotic resistance, and disease of matrix. He is interested in elucidating molecular bases for disease through the design and synthesis of molecular probes, which often have the potential to be used in new drugs to treat intractable human diseases. Mobashery has made discoveries on the intricate processes that certain bacteria employ in recycling the cell wall, a critical entity for cell survival and the one with which antibiotics are designed to interfere. Mobashery also led the investigation of the complex mechanisms that methicillin-resistant Staphylococcus aureus (MRSA) has devised to become an insidious bacterial pathogen; MRSA is now a major global health threat, killing an estimated 19,000 people each year in the United States alone.
Mobashery's work on diseases of matrix spans seemingly disparate diseases such as stroke, diabetic wound healing and idiopathic pulmonary fibrosis. The emphasis in the lab on these diseases centers on understanding of how the disease develops and progresses, as well as addressing them by pharmacological intervention.
A fellow of the American Association for the Advancement of Science, Mobashery has published more than 285 scientific papers and holds 13 patents for his discoveries. A fellow of the American Association for the Advancement of Science, Mobashery was the recipient of the Astellas USA Foundation Award of the American Chemical Society in 2007. He was the recipient of the Research Achievement Award for 2012 by the University of Notre Dame.
Contact Professor Mobashery.
Visit his website.
The Navari Professorship was endowed by Dr. Rudolph “Rudy” Navari (’66) and his wife, Jane. Dr. Navari is a practicing oncologist and former director of the Walther Cancer Research Center at Notre Dame. In 2005, he was appointed to the position of assistant dean and director of Indiana University School of Medicine-South Bend. He joined the World Health Organization in 2014 and now serves as director of the Cancer Care Program of Central and South America.